The next functions occurred in < two% of patients in managed clinical trials; a causal romantic relationship to VIAGRA is uncertain. Claimed functions include things like People using a plausible relation to drug use; omitted are minimal activities and experiences way too imprecise to be meaningful:
Know the medicines you are taking. Continue to keep a list of them to show for your Health care company and pharmacist any time you have a new medicine.
Physicians should advise people to prevent utilization of all PDE5 inhibitors, such as VIAGRA, and find health-related notice while in the party of the sudden loss of eyesight in one or both eyes. These an event could be a indication of non-arteritic anterior ischemic optic neuropathy (NAION), a explanation for diminished eyesight which include probable everlasting lack of vision, that's been described rarely post-marketing and advertising in temporal association with the use of all PDE5 inhibitors. It truly is impossible to determine no matter whether these activities are linked on to the use of PDE5 inhibitors or to other components.
Very similar values for pharmacokinetic parameters were being witnessed in regular volunteers and while in the individual inhabitants, using a populace pharmacokinetic method.
Though sildenafil enhances some markers of disease in those with pulmonary arterial hypertension, it does not surface to affect the risk of Demise or really serious Uncomfortable side effects.[twenty]
This metabolite features a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 close to 50% on the father or mother drug. Plasma concentrations of the metabolite are about 40% of People found for sildenafil, so the metabolite accounts for approximately 20% of sildenafil's pharmacologic results.
Use with caution in sufferers with the next underlying conditions that may be particularly delicate on the actions of vasodilators together with VIAGRA – Individuals with still left ventricular outflow obstruction (e.
Heart conditions: For those who have or have experienced heart problems or perhaps a heart attack or stroke, speak to your doctor ahead of taking any medication for erectile dysfunction. If upper body pains, dizziness, or nausea are expert throughout intercourse, end the exertion and tell your physician.
VIAGRA might be taken with or devoid of food. If you take VIAGRA following a high fat food (for instance a cheeseburger and french fries), VIAGRA may consider a bit for a longer time to begin Operating
Evaluation of the safety databases from controlled clinical trials confirmed no evident variance in adverse reactions in sufferers using VIAGRA with and without having anti-hypertensive medication.
Injection Liquid. Sildenafil injection is usually offered by a healthcare supplier within a clinic or clinic. You won't retail store it at home.
The security and efficacy of mixtures of VIAGRA with other PDE5 Inhibitors, which include REVATIO or other pulmonary arterial hypertension (PAH) therapies containing sildenafil, or other remedies for erectile dysfunction have not been examined.
A lessen dosage of Viagra is safer for some people. This is often because of particular things, like possessing precise healthcare problems. These things consist of:
It really is check here not possible to ascertain no matter whether these situations are associated directly to the use of PDE5 inhibitors, towards the individual's underlying vascular chance things or anatomical defects, to a combination of these elements, or to other aspects [see WARNINGS AND Safeguards and Individual Data].